Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN) (N-Term) Peptid
KNSTRN
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN1542206
Kurzübersicht für Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN) (N-Term) Peptid (ABIN1542206)
Target
KNSTRN
(Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequenz
- YRKFLFETQA ADLAGGTTVA AGNLLNESEK DCGQDRRAPG VQPCRLVTMT
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-C15orf23 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
-
Hintergrund
-
C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Alias Symbols: SKAP, TRAF4AF1, C15orf23
Protein Size: 316 -
Molekulargewicht
- 35 kDa
-
Gen-ID
- 90417
-
NCBI Accession
- NM_033286, NP_150628
-
UniProt
- Q9Y448
Target
-
Sie sind hier:
